Zirconocene-catalyzed reactions of alkenyl-substituted enol ethers.

Palladium-catalyzed enantioselective cyclization of silyloxy-1,6-enynes.

Transition-metal-catalyzed cycloisomerization and cyclization reactions of enynes have emerged as powerful methods for the construction of heteroand carbocyclic compounds.1 More recently, enantioselective cycloisomerization of 1,6and 1,7-enynes has been employed in the preparation of enantioenriched 1,4-diene containing structures.2-4 Despite its potential utility, the related enantioselective ...

Gold-catalyzed efficient formation of alkenyl enol esters/carbonates from trimethylsilylmethyl-substituted propargyl esters/carbonates.

A gold-catalyzed efficient method for the preparation of alkenyl enol esters/carbonates is developed. Besides the mild reaction conditions and high catalytic efficiency, the excellent E-selectivity of the nonenolic double bond is remarkable.

Asymmetric hetero-ene reactions of trimethylsilyl enol ethers catalyzed by tridentate Schiff base chromium(III) complexes.

Facile isomerization of silyl enol ethers catalyzed by triflic imide and its application to one-pot isomerization–(2 + 2) cycloaddition

A triflic imide (Tf(2)NH) catalyzed isomerization of kinetically favourable silyl enol ethers into thermodynamically stable ones was developed. We also demonstrated a one-pot catalytic reaction consisting of (2 + 2) cycloaddition and isomerization. In the reaction sequence, Tf(2)NH catalyzes both of the reactions.

Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes.

The application of chiral sulfinamides and achiral sulfonic acids as a cocatalyst system for enantioselective protonation reactions is described. Structurally simple, easily accessible sulfinamides were found to induce moderate-to-high ee's in the formation of 2-aryl-substituted cycloalkanones from the corresponding trimethylsilyl enol ethers.